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BMCBI
2010
115views more  BMCBI 2010»
14 years 9 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2007
160views more  BMCBI 2007»
14 years 9 months ago
Establishing a major cause of discrepancy in the calibration of Affymetrix GeneChips
Background: Affymetrix GeneChips are a popular platform for performing whole-genome experiments on the transcriptome. There are a range of different calibration steps, and users a...
Andrew P. Harrison, Caroline E. Johnston, Christin...
BMCBI
2006
128views more  BMCBI 2006»
14 years 9 months ago
Comparative assessment of performance and genome dependence among phylogenetic profiling methods
Background: The rapidly increasing speed with which genome sequence data can be generated will be accompanied by an exponential increase in the number of sequenced eukaryotes. Wit...
Evan S. Snitkin, Adam M. Gustafson, Joseph C. Mell...
RECOMB
2004
Springer
15 years 10 months ago
Probabilistic discovery of overlapping cellular processes and their regulation
In this paper, we explore modeling overlapping biological processes. We discuss a probabilistic model of overlapping biological processes, gene membership in those processes, and ...
Alexis Battle, Eran Segal, Daphne Koller
ISBRA
2007
Springer
15 years 3 months ago
GFBA: A Biclustering Algorithm for Discovering Value-Coherent Biclusters
Clustering has been one of the most popular approaches used in gene expression data analysis. A clustering method is typically used to partition genes according to their similarity...
Xubo Fei, Shiyong Lu, Horia F. Pop, Lily R. Liang