639 search results - page 98 / 128 » Identifying clusters of functionally related genes in genome... |
BMCBI
2002
14 years 9 months ago
2002
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
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BMCBI
2008
14 years 9 months ago
2008
eraction networks. In this abstract, we extend this approach by mining functional flow patterns for the purpose of detecting small-sized modules for specific functions. Methods Our...
BIBM
2009
IEEE
15 years 4 months ago
2009
IEEE
Background: In eukaryotes, alternative splicing often generates multiple splice variants from a single gene. Here weexplore the use of RNA sequencing (RNA-Seq) datasets to address...
BCB
2010
14 years 4 months ago
2010
Network-based genome-wide association studies (NWAS) utilize the molecular interactions between genes and functional pathways in biomarker identification. This study presents a no...
BMCBI
2010
14 years 9 months ago
2010
Background: Polymorphic variants and mutations disrupting canonical splicing isoforms are among the leading causes of human hereditary disorders. While there is a substantial evid...