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BMCBI
2010
131views more  BMCBI 2010»
13 years 6 months ago
FACT: Functional annotation transfer between proteins with similar feature architectures
Background: The increasing number of sequenced genomes provides the basis for exploring the genetic and functional diversity within the tree of life. Only a tiny fraction of the e...
Tina Koestler, Arndt von Haeseler, Ingo Ebersberge...
BMCBI
2010
189views more  BMCBI 2010»
13 years 6 months ago
High quality protein sequence alignment by combining structural profile prediction and profile alignment using SABERTOOTH
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
Florian Teichert, Jonas Minning, Ugo Bastolla, Mar...
RECOMB
1999
Springer
13 years 10 months ago
Fast detection of common geometric substructure in proteins
We consider the problem of identifying common three-dimensional substructures between proteins. Our method is based on comparing the shape of the α-carbon backbone structures of ...
L. Paul Chew, Daniel P. Huttenlocher, Klara Kedem,...
ALMOB
2008
82views more  ALMOB 2008»
13 years 6 months ago
Protein sequence and structure alignments within one framework
Background: Protein structure alignments are usually based on very different techniques to sequence alignments. We propose a method which treats sequence, structure and even combi...
Gundolf Schenk, Thomas Margraf, Andrew E. Torda
ISBI
2006
IEEE
14 years 7 months ago
A novel approximate inference approach to automated classification of protein subcellular location patterns in multi-cell images
The subcellular location of proteins is most often determined by visual interpretation of fluorescence microscope images. In recent years, automated systems have been developed so...
Shann-Ching Chen, Geoffrey J. Gordon, Robert F. Mu...