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BMCBI
2010
109views more  BMCBI 2010»
15 years 6 months ago
Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2008
82views more  BMCBI 2008»
15 years 6 months ago
Envelope: interactive software for modeling and fitting complex isotope distributions
Background: An important aspect of proteomic mass spectrometry involves quantifying and interpreting the isotope distributions arising from mixtures of macromolecules with differe...
Michael T. Sykes, James R. Williamson
BMCBI
2004
146views more  BMCBI 2004»
15 years 6 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
TMI
1998
137views more  TMI 1998»
15 years 6 months ago
Dynamic Imaging and Tracer Kinetic Modeling for Emission Tomography Using Rotating Detectors
— When performing dynamic studies using emission tomography the tracer distribution changes during acquisition of a single set of projections. This is particularly true for some ...
Chi-Hoi Lau, David Dagan Feng, Brian F. Hutton, Da...
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ISBI
2009
IEEE
16 years 1 months ago
Cell Tracking and Segmentation in Electron Microscopy Images Using Graph Cuts
Understanding neural connectivity and structures in the brain requires detailed 3D anatomical models, and such an understanding is essential to the study of the nervous system. Ho...
Huei-Fang Yang, Yoonsuck Choe