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BMCBI
2010
135views more  BMCBI 2010»
15 years 4 months ago
Quadratic variance models for adaptively preprocessing SELDI-TOF mass spectrometry data
Background: Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI) is a proteomics tool for biomarker discovery and other high throughput applicatio...
Vincent A. Emanuele II, Brian M. Gurbaxani
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BMCBI
2008
93views more  BMCBI 2008»
15 years 4 months ago
Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throug
Background: The recent emergence of high-throughput automated image acquisition technologies has forever changed how cell biologists collect and analyze data. Historically, the in...
Zheng Yin, Xiaobo Zhou, Chris Bakal, Fuhai Li, You...
BMCBI
2008
105views more  BMCBI 2008»
15 years 4 months ago
A Bayesian method for calculating real-time quantitative PCR calibration curves using absolute plasmid DNA standards
Background: In real-time quantitative PCR studies using absolute plasmid DNA standards, a calibration curve is developed to estimate an unknown DNA concentration. However, potenti...
Mano Sivaganesan, Shawn Seifring, Manju Varma, Ric...
BMCBI
2008
130views more  BMCBI 2008»
15 years 4 months ago
FAF-Drugs2: Free ADME/tox filtering tool to assist drug discovery and chemical biology projects
Background: Drug discovery and chemical biology are exceedingly complex and demanding enterprises. In recent years there are been increasing awareness about the importance of pred...
David Lagorce, Olivier Sperandio, Hervé Gal...
EOR
2008
123views more  EOR 2008»
15 years 4 months ago
Fixed versus flexible production systems: A real options analysis
In this work, we address investment decisions in production systems by using real options. As is standard in literature, the stochastic variable is assumed to be normally distribu...
Dalila B. M. M. Fontes
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