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BMCBI
2006
174views more  BMCBI 2006»
14 years 10 months ago
Genome wide prediction of protein function via a generic knowledge discovery approach based on evidence integration
Background: The automation of many common molecular biology techniques has resulted in the accumulation of vast quantities of experimental data. One of the major challenges now fa...
Jianghui Xiong, Simon Rayner, Kunyi Luo, Yinghui L...
EOR
2006
148views more  EOR 2006»
14 years 10 months ago
Pareto ant colony optimization with ILP preprocessing in multiobjective project portfolio selection
One of the most important, common and critical management issues lies in determining the "best" project portfolio out of a given set of investment proposals. As this dec...
Karl F. Doerner, Walter J. Gutjahr, Richard F. Har...
BMCBI
2007
94views more  BMCBI 2007»
14 years 10 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
BMCBI
2007
216views more  BMCBI 2007»
14 years 10 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos
BMCBI
2007
167views more  BMCBI 2007»
14 years 10 months ago
MindSeer: a portable and extensible tool for visualization of structural and functional neuroimaging data
Background: Three-dimensional (3-D) visualization of multimodality neuroimaging data provides a powerful technique for viewing the relationship between structure and function. A n...
Eider B. Moore, Andrew V. Poliakov, Peter Lincoln,...