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BMCBI
2008
84views more  BMCBI 2008»
14 years 9 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....
COMPUTER
2008
86views more  COMPUTER 2008»
14 years 9 months ago
Supporting Acquisition of Basic Skills
ors induce aptitudes: abstract skills and knowledge. Mentors foster attitudes: social skills and graces. In my experience of school, starting 70 years or so ago, quite regimented i...
W. Neville Holmes
CSCW
2008
ACM
14 years 9 months ago
Context-linked virtual assistants for distributed teams: an astrophysics case study
There is a growing need for distributed teams to analyze complex and dynamic data streams and make critical decisions under time pressure. Via a case study, we discuss potential g...
Sarah S. Poon, Rollin C. Thomas, Cecilia R. Aragon...
BMCBI
2007
136views more  BMCBI 2007»
14 years 9 months ago
Comparison of protein structures by growing neighborhood alignments
Background: Design of protein structure comparison algorithm is an important research issue, having far reaching implications. In this article, we describe a protein structure com...
Sourangshu Bhattacharya, Chiranjib Bhattacharyya, ...
IJBRA
2007
120views more  IJBRA 2007»
14 years 9 months ago
The myGrid ontology: bioinformatics service discovery
: In this paper we explore issues in the development of the my Grid ontology, which is an OWL ontology designed to support service discovery through service annotation. There are c...
Katy Wolstencroft, Pinar Alper, Duncan Hull, Chris...