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BMCBI
2006
119views more  BMCBI 2006»
14 years 9 months ago
LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Guoli Wang, Andrew V. Kossenkov, Michael F. Ochs
JMLR
2010
147views more  JMLR 2010»
14 years 4 months ago
Image Denoising with Kernels Based on Natural Image Relations
A successful class of image denoising methods is based on Bayesian approaches working in wavelet representations. The performance of these methods improves when relations among th...
Valero Laparra, Juan Gutierrez, Gustavo Camps-Vall...
BMCBI
2008
118views more  BMCBI 2008»
14 years 9 months ago
Virtual screening of GPCRs: An in silico chemogenomics approach
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Laurent Jacob, Brice Hoffmann, Véronique St...
BMCBI
2008
132views more  BMCBI 2008»
14 years 9 months ago
Clustering ionic flow blockade toggles with a Mixture of HMMs
Background: Ionic current blockade signal processing, for use in nanopore detection, offers a promising new way to analyze single molecule properties with potential implications f...
Alexander G. Churbanov, Stephen Winters-Hilt
IUI
2009
ACM
15 years 6 months ago
Detecting and correcting user activity switches: algorithms and interfaces
The TaskTracer system allows knowledge workers to define a set of activities that characterize their desktop work. It then associates with each user-defined activity the set of ...
Jianqiang Shen, Jed Irvine, Xinlong Bao, Michael G...