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BMCBI
2007
141views more  BMCBI 2007»
14 years 10 months ago
Using structural motif descriptors for sequence-based binding site prediction
Background: Many protein sequences are still poorly annotated. Functional characterization of a protein is often improved by the identification of its interaction partners. Here, ...
Andreas Henschel, Christof Winter, Wan Kyu Kim, Mi...
DATAMINE
2002
147views more  DATAMINE 2002»
14 years 9 months ago
Discretization: An Enabling Technique
Discrete values have important roles in data mining and knowledge discovery. They are about intervals of numbers which are more concise to represent and specify, easier to use and ...
Huan Liu, Farhad Hussain, Chew Lim Tan, Manoranjan...
BMCBI
2008
134views more  BMCBI 2008»
14 years 10 months ago
Clustering cancer gene expression data: a comparative study
Background The use of clustering methods for the discovery of cancer subtypes has drawn a great deal of attention in the scientific community. While bioinformaticians have propose...
Marcílio Carlos Pereira de Souto, Ivan G. C...
CORR
2006
Springer
153views Education» more  CORR 2006»
14 years 10 months ago
Genetic Programming, Validation Sets, and Parsimony Pressure
Fitness functions based on test cases are very common in Genetic Programming (GP). This process can be assimilated to a learning task, with the inference of models from a limited n...
Christian Gagné, Marc Schoenauer, Marc Pari...
BMCBI
2010
146views more  BMCBI 2010»
14 years 10 months ago
Nonnegative principal component analysis for mass spectral serum profiles and biomarker discovery
Background: As a novel cancer diagnostic paradigm, mass spectroscopic serum proteomic pattern diagnostics was reported superior to the conventional serologic cancer biomarkers. Ho...
Henry Han