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BIODATAMINING
2008
163views more  BIODATAMINING 2008»
14 years 11 months ago
Multivariate profiling of neurodegeneration-associated changes in a subcellular compartment of neurons via image processing
Background: Dysfunction in the endolysosome, a late endosomal to lysosomal degradative intracellular compartment, is an early hallmark of some neurodegenerative diseases, in parti...
Saravana K. Kumarasamy, Yunshi Wang, Vignesh Viswa...
BMCBI
2010
130views more  BMCBI 2010»
14 years 11 months ago
The behaviour of random forest permutation-based variable importance measures under predictor correlation
Background: Random forests (RF) have been increasingly used in applications such as genome-wide association and microarray studies where predictor correlation is frequently observ...
Kristin K. Nicodemus, James D. Malley, Carolin Str...
BMCBI
2010
162views more  BMCBI 2010»
14 years 11 months ago
Moara: a Java library for extracting and normalizing gene and protein mentions
Background: Gene/protein recognition and normalization are important preliminary steps for many biological text mining tasks, such as information retrieval, protein-protein intera...
Mariana L. Neves, José María Carazo,...
BMCBI
2010
116views more  BMCBI 2010»
14 years 11 months ago
permGPU: Using graphics processing units in RNA microarray association studies
Background: Many analyses of microarray association studies involve permutation, bootstrap resampling and crossvalidation, that are ideally formulated as embarrassingly parallel c...
Ivo D. Shterev, Sin-Ho Jung, Stephen L. George, Ko...
BMCBI
2010
150views more  BMCBI 2010»
14 years 11 months ago
Evolutionary rates at codon sites may be used to align sequences and infer protein domain function
Background: Sequence alignments form part of many investigations in molecular biology, including the determination of phylogenetic relationships, the prediction of protein structu...
Pierre M. Durand, Scott Hazelhurst, Theresa L. Coe...
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