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BMCBI
2010
100views more  BMCBI 2010»
14 years 11 months ago
Scaffold filling, contig fusion and comparative gene order inference
Background: There has been a trend in increasing the phylogenetic scope of genome sequencing without finishing the sequence of the genome. Increasing numbers of genomes are being ...
Adriana Muñoz, Chunfang Zheng, Qian Zhu, Vi...
BMCBI
2010
185views more  BMCBI 2010»
14 years 11 months ago
ABCtoolbox: a versatile toolkit for approximate Bayesian computations
Background: The estimation of demographic parameters from genetic data often requires the computation of likelihoods. However, the likelihood function is computationally intractab...
Daniel Wegmann, Christoph Leuenberger, Samuel Neue...
BMCBI
2010
105views more  BMCBI 2010»
14 years 10 months ago
Evaluation of fecal mRNA reproducibility via a marginal transformed mixture modeling approach
Background: Developing and evaluating new technology that enables researchers to recover gene-expression levels of colonic cells from fecal samples could be key to a non-invasive ...
Nysia I. George, Joanne R. Lupton, Nancy D. Turner...
BMCBI
2010
144views more  BMCBI 2010»
14 years 10 months ago
Finding sRNA generative locales from high-throughput sequencing data with NiBLS
Background: Next-generation sequencing technologies allow researchers to obtain millions of sequence reads in a single experiment. One important use of the technology is the seque...
Daniel MacLean, Vincent Moulton, David J. Studholm...
BMCBI
2008
92views more  BMCBI 2008»
14 years 10 months ago
Proteochemometric modeling of HIV protease susceptibility
Background: A major obstacle in treatment of HIV is the ability of the virus to mutate rapidly into drug-resistant variants. A method for predicting the susceptibility of mutated ...
Maris Lapinsh, Martin Eklund, Ola Spjuth, Peteris ...
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