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BMCBI
2010
105views more  BMCBI 2010»
15 years 1 months ago
The Neural/Immune Gene Ontology: clipping the Gene Ontology for neurological and immunological systems
Background: The Gene Ontology (GO) is used to describe genes and gene products from many organisms. When used for functional annotation of microarray data, GO is often slimmed by ...
Nophar Geifman, Alon Monsonego, Eitan Rubin
BMCBI
2007
133views more  BMCBI 2007»
15 years 1 months ago
Semantic integration to identify overlapping functional modules in protein interaction networks
Background: The systematic analysis of protein-protein interactions can enable a better understanding of cellular organization, processes and functions. Functional modules can be ...
Young-Rae Cho, Woochang Hwang, Murali Ramanathan, ...
BMCBI
2008
178views more  BMCBI 2008»
15 years 1 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
BMCBI
2008
170views more  BMCBI 2008»
15 years 1 months ago
A genetic approach for building different alphabets for peptide and protein classification
Background: In this paper, it is proposed an optimization approach for producing reduced alphabets for peptide classification, using a Genetic Algorithm. The classification task i...
Loris Nanni, Alessandra Lumini
DSS
2008
103views more  DSS 2008»
15 years 1 months ago
Explaining clinical decisions by extracting regularity patterns
When solving clinical decision-making problems with modern graphical decision-theoretic models such as influence diagrams, we obtain decision tables with optimal decision alternat...
Concha Bielza, Juan A. Fernández del Pozo, ...