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150
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BMCBI
2007
15 years 4 months ago
2007
Background: Serial analysis of gene expression (SAGE) is used to obtain quantitative snapshots of the transcriptome. These profiles are count-based and are assumed to follow a Bin...
154
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BMCBI
2007
15 years 4 months ago
2007
Background: Domains are the basic functional units of proteins. It is believed that protein-protein interactions are realized through domain interactions. Revealing multi-domain c...
151
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BMCBI
2007
15 years 4 months ago
2007
Background: Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of micr...
149
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BMCBI
2008
15 years 4 months ago
2008
Background: The detection of conserved motifs in promoters of orthologous genes (phylogenetic footprints) has become a common strategy to predict cis-acting regulatory elements. S...
138
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BMCBI
2010
15 years 4 months ago
2010
Background: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostabilit...