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BMCBI
2010
134views more  BMCBI 2010»
15 years 4 months ago
BayesMotif: de novo protein sorting motif discovery from impure datasets
Background: Protein sorting is the process that newly synthesized proteins are transported to their target locations within or outside of the cell. This process is precisely regul...
Jianjun Hu, Fan Zhang
BMCBI
2007
91views more  BMCBI 2007»
15 years 4 months ago
A mass accuracy sensitive probability based scoring algorithm for database searching of tandem mass spectrometry data
Background: Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) has become one of the most used tools in mass spectrometry based proteomics. Various algorithms ...
Hua Xu, Michael A. Freitas
BMCBI
2007
166views more  BMCBI 2007»
15 years 4 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
BMCBI
2008
134views more  BMCBI 2008»
15 years 4 months ago
Stability analysis of mixtures of mutagenetic trees
Background: Mixture models of mutagenetic trees are evolutionary models that capture several pathways of ordered accumulation of genetic events observed in different subsets of pa...
Jasmina Bogojeska, Thomas Lengauer, Jörg Rahn...
BMCBI
2008
105views more  BMCBI 2008»
15 years 4 months ago
Novel computational methods for increasing PCR primer design effectiveness in directed sequencing
Background: Polymerase chain reaction (PCR) is used in directed sequencing for the discovery of novel polymorphisms. As the first step in PCR directed sequencing, effective PCR pr...
Kelvin Li, Anushka Brownley, Timothy B. Stockwell,...
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