Background: The rapid growth of protein-protein interaction (PPI) data has led to the emergence of PPI network analysis. Despite advances in high-throughput techniques, the intera...
Background: Protein-protein interactions play a critical role in protein function. Completion of many genomes is being followed rapidly by major efforts to identify interacting pr...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...
Protein-protein interactions (PPI) play a key role in many biological systems. Over the past few years, an explosion in availability of functional biological data obtained from hi...
Background: Reliable prediction of antibody, or B-cell, epitopes remains challenging yet highly desirable for the design of vaccines and immunodiagnostics. A correlation between a...
Julia V. Ponomarenko, Huynh-Hoa Bui, Wei Li, Nicho...
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...