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BMCBI
2010
136views more  BMCBI 2010»
14 years 11 months ago
A hub-attachment based method to detect functional modules from confidence-scored protein interactions and expression profiles
Background: Many research results show that the biological systems are composed of functional modules. Members in the same module usually have common functions. This is useful inf...
Chia-Hao Chin, Shu-Hwa Chen, Chin-Wen Ho, Ming-Tat...
BIBM
2010
IEEE
158views Bioinformatics» more  BIBM 2010»
14 years 9 months ago
Protein-protein interaction prediction via Collective Matrix Factorization
Abstract--Protein-protein interactions (PPI) play an important role in cellular processes and metabolic processes within a cell. An important task is to determine the existence of ...
Qian Xu, Evan Wei Xiang, Qiang Yang
BMCBI
2007
144views more  BMCBI 2007»
14 years 11 months ago
InPrePPI: an integrated evaluation method based on genomic context for predicting protein-protein interactions in prokaryotic ge
Background: Although many genomic features have been used in the prediction of proteinprotein interactions (PPIs), frequently only one is used in a computational method. After rea...
Jingchun Sun, Yan Sun, Guohui Ding, Qi Liu, Chuan ...
BMCBI
2010
150views more  BMCBI 2010»
14 years 11 months ago
MCL-CAw: a refinement of MCL for detecting yeast complexes from weighted PPI networks by incorporating core-attachment structure
Background: The reconstruction of protein complexes from the physical interactome of organisms serves as a building block towards understanding the higher level organization of th...
Sriganesh Srihari, Kang Ning, Hon Wai Leong
BMCBI
2007
157views more  BMCBI 2007»
14 years 11 months ago
Statistical learning of peptide retention behavior in chromatographic separations: a new kernel-based approach for computational
Background: High-throughput peptide and protein identification technologies have benefited tremendously from strategies based on tandem mass spectrometry (MS/MS) in combination wi...
Nico Pfeifer, Andreas Leinenbach, Christian G. Hub...