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ASPLOS
1994
ACM
15 years 3 months ago
Compiler Optimizations for Improving Data Locality
In the past decade, processor speed has become significantly faster than memory speed. Small, fast cache memories are designed to overcome this discrepancy, but they are only effe...
Steve Carr, Kathryn S. McKinley, Chau-Wen Tseng
BMCBI
2007
109views more  BMCBI 2007»
14 years 11 months ago
Computational RNA secondary structure design: empirical complexity and improved methods
Background: We investigate the empirical complexity of the RNA secondary structure design problem, that is, the scaling of the typical difficulty of the design task for various cl...
Rosalía Aguirre-Hernández, Holger H....
BMCBI
2006
124views more  BMCBI 2006»
14 years 11 months ago
Network-based de-noising improves prediction from microarray data
Background: Prediction of human cell response to anti-cancer drugs (compounds) from microarray data is a challenging problem, due to the noise properties of microarrays as well as...
Tsuyoshi Kato, Yukio Murata, Koh Miura, Kiyoshi As...
BMCBI
2006
111views more  BMCBI 2006»
14 years 11 months ago
Using ESTs to improve the accuracy of de novo gene prediction
Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Ge...
Chaochun Wei, Michael R. Brent
BMCBI
2010
110views more  BMCBI 2010»
14 years 10 months ago
Improvements to previous algorithms to predict gene structure and isoform concentrations using Affymetrix Exon arrays
Background: Exon arrays provide a way to measure the expression of different isoforms of genes in an organism. Most of the procedures to deal with these arrays are focused on gene...
Miguel A. Anton, Ander Aramburu, Angel Rubio