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BMCBI
2006
143views more  BMCBI 2006»
14 years 9 months ago
Application of protein structure alignments to iterated hidden Markov model protocols for structure prediction
Background: One of the most powerful methods for the prediction of protein structure from sequence information alone is the iterative construction of profile-type models. Because ...
Eric D. Scheeff, Philip E. Bourne
BMCBI
2007
142views more  BMCBI 2007»
14 years 10 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...
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BMCBI
2007
130views more  BMCBI 2007»
14 years 10 months ago
HMM-ModE - Improved classification using profile hidden Markov models by optimising the discrimination threshold and modifying e
Background: Profile Hidden Markov Models (HMM) are statistical representations of protein families derived from patterns of sequence conservation in multiple alignments and have b...
Prashant K. Srivastava, Dhwani K. Desai, Soumyadee...
BMCBI
2006
85views more  BMCBI 2006»
14 years 9 months ago
On single and multiple models of protein families for the detection of remote sequence relationships
Background: The detection of relationships between a protein sequence of unknown function and a sequence whose function has been characterised enables the transfer of functional a...
James A. Casbon, Mansoor A. S. Saqi
ICIP
2009
IEEE
15 years 10 months ago
Bim: Image Matching Using Biological Gene Sequence Alignment
Matching two images with similar contents is one of the most fundamental tasks in image processing. Due to its importance, in recent years, many novel techniques have been propose...