197 search results - page 22 / 40 » Improving pairwise sequence alignment accuracy using near-op... |
114
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BMCBI
2011
14 years 4 months ago
2011
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
BIBE
2006
IEEE
15 years 3 months ago
2006
IEEE
DNA sequence alignment is a critical step in identifying homology between organisms. The most widely used alignment program, ClustalW, is known to suffer from the local minima pro...
101
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BMCBI
2008
14 years 10 months ago
2008
Background: For many types of analyses, data about gene structure and locations of non-coding regions of genes are required. Although a vast amount of genomic sequence data is ava...
BMCBI
2011
14 years 4 months ago
2011
Background: We present a novel method to encode ambiguously aligned regions in fixed multiple sequence alignments by ‘Pairwise Identity and Cost Scores Ordination’ (PICS-Ord)....
BIBE
2005
IEEE
15 years 3 months ago
2005
IEEE
We have recently demonstrated (La et al, Proteins, 58:2005) that sequence fragments approximating the overall familial phylogeny, called phylogenetic motifs (PMs), represent a pro...