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BMCBI
2006
126views more  BMCBI 2006»
14 years 9 months ago
A Regression-based K nearest neighbor algorithm for gene function prediction from heterogeneous data
Background: As a variety of functional genomic and proteomic techniques become available, there is an increasing need for functional analysis methodologies that integrate heteroge...
Zizhen Yao, Walter L. Ruzzo
BMCBI
2010
88views more  BMCBI 2010»
14 years 9 months ago
Proteome scanning to predict PDZ domain interactions using support vector machines
Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...
Shirley Hui, Gary D. Bader
BIOADIT
2004
Springer
15 years 3 months ago
Movement Generation and Control with Generic Neural Microcircuits
Abstract. Simple linear readouts from generic neural microcircuit models can be trained to generate and control basic movements, e.g., reaching with an arm to various target points...
Prashant Joshi, Wolfgang Maass
AAAI
2007
14 years 12 months ago
A Randomized String Kernel and Its Application to RNA Interference
String kernels directly model sequence similarities without the necessity of extracting numerical features in a vector space. Since they better capture complex traits in the seque...
Shibin Qiu, Terran Lane, Ljubomir J. Buturovic
86
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GECCO
2006
Springer
172views Optimization» more  GECCO 2006»
15 years 1 months ago
Multi-objective optimisation of the protein-ligand docking problem in drug discovery
The pharmaceutical industry is facing an ever-increasing demand to discover novel drugs that are more effective and safer than existing ones. The industry faces huge problem in im...
A. Oduguwa, A. Tiwari, S. Fiorentino, R. Roy