Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structur...
Indirect branches have become increasingly common in modular programs written in modern object-oriented languages and virtualmachine based runtime systems. Unfortunately, the pred...
As processor architectures have increased their reliance on speculative execution to improve performance, the importance of accurate prediction of what to execute speculatively ha...
Energy efficiency and positional accuracy are often contradictive goals. We propose to decrease power consumption without sacrificing significant accuracy by developing an energy-...