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BMCBI
2010
190views more  BMCBI 2010»
14 years 11 months ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...
75
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NAR
2006
91views more  NAR 2006»
14 years 11 months ago
YOGY: a web-based, integrated database to retrieve protein orthologs and associated Gene Ontology terms
We present YOGY a web-based resource for orthologous proteins from nine eukaryotic organisms: Homo sapiens, Mus musculus, Rattus norvegicus, Arabidopsis thaliana, Drosophila melan...
Christopher J. Penkett, James A. Morris, Valerie W...
84
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BMCBI
2010
139views more  BMCBI 2010»
14 years 11 months ago
CMASA: an accurate algorithm for detecting local protein structural similarity and its application to enzyme catalytic site anno
Background: The rapid development of structural genomics has resulted in many "unknown function" proteins being deposited in Protein Data Bank (PDB), thus, the functiona...
Gong-Hua Li, Jing-Fei Huang
BIBM
2008
IEEE
125views Bioinformatics» more  BIBM 2008»
14 years 11 months ago
Systems Biology via Redescription and Ontologies (III): Protein Classification Using Malaria Parasite's Temporal Transcriptomic
This paper addresses the protein classification problem, and explores how its accuracy can be improved by using information from time-course gene expression data. The methods are ...
Antonina Mitrofanova, Samantha Kleinberg, Jane Car...
PRIB
2009
Springer
187views Bioinformatics» more  PRIB 2009»
15 years 4 months ago
Semi-supervised Prediction of Protein Interaction Sentences Exploiting Semantically Encoded Metrics
Protein-protein interaction (PPI) identification is an integral component of many biomedical research and database curation tools. Automation of this task through classification ...
Tamara Polajnar, Mark A. Girolami