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SAC
2006
ACM
15 years 3 months ago
Protein classification using transductive learning on phylogenetic profiles
Phylogenetic profiles of proteins − strings of ones and zeros encoding respectively the presence and absence of proteins in a group of genomes − have recently been used to iden...
Roger A. Craig, Li Liao
NCA
2007
IEEE
14 years 9 months ago
A data reduction approach for resolving the imbalanced data issue in functional genomics
Learning from imbalanced data occurs frequently in many machine learning applications. One positive example to thousands of negative instances is common in scientific applications...
Kihoon Yoon, Stephen Kwek
81
Voted
BMCBI
2008
114views more  BMCBI 2008»
14 years 9 months ago
Combining classifiers for improved classification of proteins from sequence or structure
Background: Predicting a protein's structural or functional class from its amino acid sequence or structure is a fundamental problem in computational biology. Recently, there...
Iain Melvin, Jason Weston, Christina S. Leslie, Wi...
SDM
2008
SIAM
121views Data Mining» more  SDM 2008»
14 years 11 months ago
Integration of Multiple Networks for Robust Label Propagation
Transductive inference on graphs such as label propagation algorithms is receiving a lot of attention. In this paper, we address a label propagation problem on multiple networks a...
Tsuyoshi Kato, Hisashi Kashima, Masashi Sugiyama
BMCBI
2005
118views more  BMCBI 2005»
14 years 9 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz