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BIOINFORMATICS
2006
134views more  BIOINFORMATICS 2006»
14 years 9 months ago
HaptenDB: a comprehensive database of haptens, carrier proteins and anti-hapten antibodies
The key requirement for successful immunochemical assay is the availability of antibodies with high specificity and desired affinity. Small molecules, when used as haptens, are no...
Mahender Kumar Singh, Shilpy Srivastava, G. P. S. ...
BMCBI
2005
132views more  BMCBI 2005»
14 years 9 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
ICML
2010
IEEE
14 years 10 months ago
Improved Local Coordinate Coding using Local Tangents
Local Coordinate Coding (LCC), introduced in (Yu et al., 2009), is a high dimensional nonlinear learning method that explicitly takes advantage of the geometric structure of the d...
Kai Yu, Tong Zhang
BMCBI
2006
108views more  BMCBI 2006»
14 years 9 months ago
Gene function classification using Bayesian models with hierarchy-based priors
We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
Babak Shahbaba, Radford M. Neal
BMCBI
2007
147views more  BMCBI 2007»
14 years 9 months ago
Hon-yaku: a biology-driven Bayesian methodology for identifying translation initiation sites in prokaryotes
Background: Computational prediction methods are currently used to identify genes in prokaryote genomes. However, identification of the correct translation initiation sites remain...
Yuko Makita, Michiel J. L. de Hoon, Antoine Danchi...