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» Improving the scaling normalization for high-density oligonu...
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BMCBI
2004
108views more  BMCBI 2004»
14 years 10 months ago
Improving the scaling normalization for high-density oligonucleotide GeneChip expression microarrays
Background: Normalization is an important step for microarray data analysis to minimize biological and technical variations. Choosing a suitable approach can be critical. The defa...
Chao Lu
94
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BMCBI
2007
180views more  BMCBI 2007»
14 years 10 months ago
Using expression arrays for copy number detection: an example from E. coli
Background: The sequencing of many genomes and tiling arrays consisting of millions of DNA segments spanning entire genomes have made high-resolution copy number analysis possible...
Dmitriy Skvortsov, Diana Abdueva, Michael E. Stitz...
81
Voted
BMCBI
2005
169views more  BMCBI 2005»
14 years 10 months ago
An adaptive method for cDNA microarray normalization
Background: Normalization is a critical step in analysis of gene expression profiles. For duallabeled arrays, global normalization assumes that the majority of the genes on the ar...
Yingdong Zhao, Ming-Chung Li, Richard Simon
BMCBI
2005
112views more  BMCBI 2005»
14 years 10 months ago
"Harshlighting" small blemishes on microarrays
Background: Microscopists are familiar with many blemishes that fluorescence images can have due to dust and debris, glass flaws, uneven distribution of fluids or surface coatings...
Mayte Suárez-Fariñas, Asifa Haider, ...
93
Voted
BMCBI
2008
128views more  BMCBI 2008»
14 years 10 months ago
Improving the prediction accuracy in classification using the combined data sets by ranks of gene expressions
Background: The information from different data sets experimented under different conditions may be inconsistent even though they are performed with the same research objectives. ...
Ki-Yeol Kim, Dong Hyuk Ki, Hei-Cheul Jeung, Hyun C...