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» In Search of Optimal Codes for DNA Computing
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RECOMB
2004
Springer
15 years 9 months ago
Designing multiple simultaneous seeds for DNA similarity search
The challenge of similarity search in massive DNA sequence databases has inspired major changes in BLAST-style alignment tools, which accelerate search by inspecting only pairs of...
Yanni Sun, Jeremy Buhler
RECOMB
2003
Springer
15 years 9 months ago
Designing seeds for similarity search in genomic DNA
Large-scale comparison of genomic DNA is of fundamental importance in annotating functional elements of genomes. To perform large comparisons efficiently, BLAST (Methods: Companio...
Jeremy Buhler, Uri Keich, Yanni Sun
75
Voted
BMCBI
2005
142views more  BMCBI 2005»
14 years 9 months ago
transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences
Background: Alignments of homologous DNA sequences are crucial for comparative genomics and phylogenetic analysis. However, multiple alignment represents a computationally difficu...
Olaf R. P. Bininda-Emonds
ISMIS
2003
Springer
15 years 2 months ago
Evolutionary Computation for Optimal Ensemble Classifier in Lymphoma Cancer Classification
Owing to the development of DNA microarray technologies, it is possible to get thousands of expression levels of genes at once. If we make the effective classification system with ...
Chanho Park, Sung-Bae Cho
ISMB
1996
14 years 10 months ago
Finding Genes in DNA Using Decision Trees and Dynamic Programming
This study demonstratesthe use of decision tree classifiers as the basis for a general gene-finding system. The system uses a dynamic programmingalgorithm that. finds the optimal ...
Steven Salzberg, Xin Chen, John Henderson, Kenneth...