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BMCBI
2008
126views more  BMCBI 2008»
14 years 9 months ago
c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
Katerina Kechris, Hao Li
BMCBI
2007
106views more  BMCBI 2007»
14 years 9 months ago
Mining prokaryotic genomes for unknown amino acids: a stop-codon-based approach
Background: Selenocysteine and pyrrolysine are the 21st and 22nd amino acids, which are genetically encoded by stop codons. Since a number of microbial genomes have been completel...
Masashi Fujita, Hisaaki Mihara, Susumu Goto, Nobuy...
FLAIRS
2007
14 years 11 months ago
Performance Analysis of Evolutionary Search with a Dynamic Restart Policy
In this work we explore how the complexity of a problem domain affects the performance of evolutionary search using a performance-based restart policy. Previous research indicates...
Michael Solano, Istvan Jonyer
BMCBI
2010
119views more  BMCBI 2010»
14 years 9 months ago
Coherent pipeline for biomarker discovery using mass spectrometry and bioinformatics
Background: Robust biomarkers are needed to improve microbial identification and diagnostics. Proteomics methods based on mass spectrometry can be used for the discovery of novel ...
Ali Al-Shahib, Raju Misra, Nadia Ahmod, Min Fang, ...
BMCBI
2006
115views more  BMCBI 2006»
14 years 9 months ago
Detecting recombination in evolving nucleotide sequences
Background: Genetic recombination can produce heterogeneous phylogenetic histories within a set of homologous genes. These recombination events can be obscured by subsequent resid...
Cheong Xin Chan, Robert G. Beiko, Mark A. Ragan