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BMCBI
2007
111views more  BMCBI 2007»
13 years 6 months ago
Modular co-evolution of metabolic networks
Background: The architecture of biological networks has been reported to exhibit high level of modularity, and to some extent, topological modules of networks overlap with known f...
Jing Zhao, Guohui Ding, Lin Tao, Hong Yu, Zhong-Ha...
BMCBI
2010
181views more  BMCBI 2010»
13 years 6 months ago
Intensity dependent estimation of noise in microarrays improves detection of differentially expressed genes
Background: In many microarray experiments, analysis is severely hindered by a major difficulty: the small number of samples for which expression data has been measured. When one ...
Amit Zeisel, Amnon Amir, Wolfgang J. Köstler,...
BMCBI
2008
84views more  BMCBI 2008»
13 years 6 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....
BMCBI
2006
149views more  BMCBI 2006»
13 years 6 months ago
Curation of viral genomes: challenges, applications and the way forward
Background: Whole genome sequence data is a step towards generating the 'parts list' of life to understand the underlying principles of Biocomplexity. Genome sequencing ...
Urmila Kulkarni-Kale, Shriram Bhosle, G. Sunitha M...
PRESENCE
2006
104views more  PRESENCE 2006»
13 years 6 months ago
Physically Realistic Virtual Surgery Using the Point-Associated Finite Field (PAFF) Approach
The generation of multimodal virtual environments for surgical training is complicated by the necessity to develop heterogeneous simulation scenarios such as surgical incision, ca...
Suvranu De, Yi-Je Lim, Manivannan Muniyandi, Manda...