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» Index-Based Approach to Similarity Search in Protein and Nuc...
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DASFAA
2005
IEEE
209views Database» more  DASFAA 2005»
15 years 3 months ago
PADS: Protein Structure Alignment Using Directional Shape Signatures
A novel approach for similarity search on the protein structure databases is proposed. PADS (Protein Alignment by Directional shape Signatures) incorporates the three dimensional ...
S. Alireza Aghili, Divyakant Agrawal, Amr El Abbad...
BMCBI
2005
124views more  BMCBI 2005»
14 years 9 months ago
Probabilistic annotation of protein sequences based on functional classifications
: One of the most evident achievements of bioinformatics is the development of methods that transfer biological knowledge from characterised proteins to uncharacterised sequences. ...
Emmanuel D. Levy, Christos A. Ouzounis, Walter R. ...
CORR
2010
Springer
144views Education» more  CORR 2010»
14 years 9 months ago
CLP-based protein fragment assembly
Abstract. The paper investigates a novel approach, based on Constraint Logic Programming (CLP), to predict the 3D conformation of a protein via fragments assembly. The fragments ar...
Alessandro Dal Palù, Agostino Dovier, Feder...
BMCBI
2006
144views more  BMCBI 2006»
14 years 9 months ago
methBLAST and methPrimerDB: web-tools for PCR based methylation analysis
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...
Filip Pattyn, Jasmien Hoebeeck, Piet Robbrecht, Ev...
BMCBI
2008
200views more  BMCBI 2008»
14 years 9 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia