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» Indexing and Searching a Mass Spectrometry Database
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BMCBI
2010
152views more  BMCBI 2010»
13 years 6 months ago
A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry
Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
Chongle Pan, Byung-Hoon Park, William H. McDonald,...
CIBCB
2009
IEEE
13 years 7 months ago
An application of the metric access methods to the mass spectrometry data
Mass spectrometry is a very popular method for protein and peptide identification nowadays. Abundance of data generated in this way grows exponentially every year and although ther...
Jiri Novák, David Hoksza
BMCBI
2010
119views more  BMCBI 2010»
13 years 6 months ago
Coherent pipeline for biomarker discovery using mass spectrometry and bioinformatics
Background: Robust biomarkers are needed to improve microbial identification and diagnostics. Proteomics methods based on mass spectrometry can be used for the discovery of novel ...
Ali Al-Shahib, Raju Misra, Nadia Ahmod, Min Fang, ...
VIS
2005
IEEE
204views Visualization» more  VIS 2005»
14 years 7 months ago
Differential Protein Expression Analysis via Liquid-Chromatography/Mass-Spectrometry Data Visualization
Differential protein expression analysis is one of the main challenges in proteomics. It denotes the search for proteins, whose encoding genes are differentially expressed under a...
Lars Linsen, Julia Löcherbach, Matthias Berth...
BMCBI
2007
86views more  BMCBI 2007»
13 years 6 months ago
Tandem mass spectrometry data quality assessment by self-convolution
Background: Many algorithms have been developed for deciphering the tandem mass spectrometry (MS) data sets. They can be essentially clustered into two classes. The first performs...
Keng Wah Choo, Wai Mun Tham