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138
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BMCBI
2005
119views more  BMCBI 2005»
15 years 3 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona
BMCBI
2005
201views more  BMCBI 2005»
15 years 3 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
134
Voted
BMCBI
2005
94views more  BMCBI 2005»
15 years 3 months ago
Visualization-based discovery and analysis of genomic aberrations in microarray data
Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...
Chad L. Myers, Xing Chen, Olga G. Troyanskaya
140
Voted
BMCBI
2004
150views more  BMCBI 2004»
15 years 3 months ago
Cross-species comparison significantly improves genome-wide prediction of cis-regulatory modules in Drosophila
Background: The discovery of cis-regulatory modules in metazoan genomes is crucial for understanding the connection between genes and organism diversity. It is important to quanti...
Saurabh Sinha, Mark D. Schroeder, Ulrich Unnerstal...
NN
2000
Springer
170views Neural Networks» more  NN 2000»
15 years 3 months ago
Synthetic brain imaging: grasping, mirror neurons and imitation
The article contributes to the quest to relate global data on brain and behavior (e.g. from PET, Positron Emission Tomography, and fMRI, functional Magnetic Resonance Imaging) to ...
Michael A. Arbib, Aude Billard, Marco Iacoboni, Er...