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» Inference Algorithms for Similarity Networks
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BMCBI
2005
169views more  BMCBI 2005»
15 years 3 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
JMLR
2008
148views more  JMLR 2008»
15 years 3 months ago
Linear-Time Computation of Similarity Measures for Sequential Data
Efficient and expressive comparison of sequences is an essential procedure for learning with sequential data. In this article we propose a generic framework for computation of sim...
Konrad Rieck, Pavel Laskov
LION
2009
Springer
112views Optimization» more  LION 2009»
15 years 9 months ago
A Graph-Based Semi-supervised Algorithm for Protein Function Prediction from Interaction Maps
Abstract. Protein function prediction represents a fundamental challenge in bioinformatics. The increasing availability of proteomics network data has enabled the development of se...
Valerio Freschi
BMCBI
2010
153views more  BMCBI 2010»
15 years 3 months ago
Metamotifs - a generative model for building families of nucleotide position weight matrices
Background: Development of high-throughput methods for measuring DNA interactions of transcription factors together with computational advances in short motif inference algorithms...
Matias Piipari, Thomas A. Down, Tim J. P. Hubbard
BMCBI
2008
116views more  BMCBI 2008»
15 years 3 months ago
IgTM: An algorithm to predict transmembrane domains and topology in proteins
Background: Due to their role of receptors or transporters, membrane proteins play a key role in many important biological functions. In our work we used Grammatical Inference (GI...
Piedachu Peris, Damián López, Marcel...