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103
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ICMLA
2010
14 years 7 months ago
Smoothing Gene Expression Using Biological Networks
Gene expression (microarray) data have been used widely in bioinformatics. The expression data of a large number of genes from small numbers of subjects are used to identify inform...
Yue Fan, Mark A. Kon, Shinuk Kim, Charles DeLisi
102
Voted
BMCBI
2007
227views more  BMCBI 2007»
14 years 9 months ago
Growing functional modules from a seed protein via integration of protein interaction and gene expression data
Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...
BMCBI
2006
149views more  BMCBI 2006»
14 years 9 months ago
HeatMapper: powerful combined visualization of gene expression profile correlations, genotypes, phenotypes and sample characteri
Background: Accurate interpretation of data obtained by unsupervised analysis of large scale expression profiling studies is currently frequently performed by visually combining s...
Roel G. W. Verhaak, Mathijs A. Sanders, Maarten A....
BMCBI
2010
115views more  BMCBI 2010»
14 years 9 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
80
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CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
15 years 2 months ago
Latent Structure Models for the Analysis of Gene Expression Data
Cluster methods have been successfully applied in gene expression data analysis to address tumor classification. By grouping tissue samples into homogeneous subsets, more systema...
Dong Hua, Dechang Chen, Xiuzhen Cheng, Abdou Youss...