The availability of entire genome sequences, coupled with genome-wide studies of gene expression, offers promise for discovering new pathways along with their regulatory programs....
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
Background: Microarray experiments examine the change in transcript levels of tens of thousands of genes simultaneously. To derive meaningful data, biologists investigate the resp...
Mayer Alvo, Zhongzhu Liu, Andrew Williams, Carole ...
Abstract. Pattern-based clustering has broad applications in microarray data analysis, customer segmentation, e-business data analysis, etc. However, pattern-based clustering often...
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...