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CSB
2005
IEEE
124views Bioinformatics» more  CSB 2005»
15 years 5 months ago
Discovering Functional Transcription Factor Binding from Superimposed Gene Networks
The availability of entire genome sequences, coupled with genome-wide studies of gene expression, offers promise for discovering new pathways along with their regulatory programs....
Matthew T. Weirauch, Joshua M. Stuart
BMCBI
2004
106views more  BMCBI 2004»
14 years 11 months ago
Spotting effect in microarray experiments
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
Tristan Mary-Huard, Jean-Jacques Daudin, Sté...
BMCBI
2010
118views more  BMCBI 2010»
14 years 12 months ago
Testing for mean and correlation changes in microarray experiments: an application for pathway analysis
Background: Microarray experiments examine the change in transcript levels of tens of thousands of genes simultaneously. To derive meaningful data, biologists investigate the resp...
Mayer Alvo, Zhongzhu Liu, Andrew Williams, Carole ...
DASFAA
2005
IEEE
137views Database» more  DASFAA 2005»
15 years 5 months ago
A General Approach to Mining Quality Pattern-Based Clusters from Microarray Data
Abstract. Pattern-based clustering has broad applications in microarray data analysis, customer segmentation, e-business data analysis, etc. However, pattern-based clustering often...
Daxin Jiang, Jian Pei, Aidong Zhang
BMCBI
2008
106views more  BMCBI 2008»
14 years 12 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...