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BIOINFORMATICS
2006
14 years 11 months ago
2006
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
105
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BMCBI
2007
14 years 11 months ago
2007
Background: Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. Computational approaches to this problem ...
BMCBI
2006
14 years 11 months ago
2006
Background: The high-density oligonucleotide microarray (GeneChip) is an important tool for molecular biological research aiming at large-scale detection of small nucleotide polym...
BMCBI
2006
14 years 11 months ago
2006
Background: Intensity values measured by Affymetrix microarrays have to be both normalized, to be able to compare different microarrays by removing non-biological variation, and s...
104
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BMCBI
2007
14 years 11 months ago
2007
Background: Extracting biological information from high-density Affymetrix arrays is a multi-step process that begins with the accurate annotation of microarray probes. Shortfalls...