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ALIFE
2008
14 years 9 months ago
Exploring the Operational Characteristics of Inference Algorithms for Transcriptional Networks by Means of Synthetic Data
The development of structure-learning algorithms for gene regulatory networks depends heavily on the availability of synthetic data sets that contain both the original network and ...
Koenraad Van Leemput, Tim Van den Bulcke, Thomas D...
CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
15 years 2 months ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
BMCBI
2006
156views more  BMCBI 2006»
14 years 9 months ago
GOFFA: Gene Ontology For Functional Analysis - A FDA Gene Ontology Tool for Analysis of Genomic and Proteomic Data
Background: Gene Ontology (GO) characterizes and categorizes the functions of genes and their products according to biological processes, molecular functions and cellular componen...
Hongmei Sun, Hong Fang, Tao Chen, Roger Perkins, W...
BMCBI
2010
122views more  BMCBI 2010»
14 years 4 months ago
Functional enrichment analyses and construction of functional similarity networks with high confidence function prediction by PF
Background: A new paradigm of biological investigation takes advantage of technologies that produce large high throughput datasets, including genome sequences, interactions of pro...
Troy Hawkins, Meghana Chitale, Daisuke Kihara
BMCBI
2010
65views more  BMCBI 2010»
14 years 9 months ago
VIPR: A probabilistic algorithm for analysis of microbial detection microarrays
Background: All infectious disease oriented clinical diagnostic assays in use today focus on detecting the presence of a single, well defined target agent or a set of agents. In r...
Adam F. Allred, Guang Wu, Tuya Wulan, Kael F. Fisc...