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» Inference of Isoforms from Short Sequence Reads
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BMCBI
2010
127views more  BMCBI 2010»
14 years 10 months ago
Deriving enzymatic and taxonomic signatures of metagenomes from short read data
Background: We propose a method for deriving enzymatic signatures from short read metagenomic data of unknown species. The short read data are converted to six pseudo-peptide cand...
Uri Weingart, Erez Persi, Uri Gophna, David Horn
BICOB
2009
Springer
15 years 4 months ago
Assembly of Large Genomes from Paired Short Reads
The de novo assembly of genomes from high-throughput short reads is an active area of research. Several promising methods have been recently developed, with applicability mainly re...
Benjamin G. Jackson, Patrick S. Schnable, Srinivas...
RECOMB
2008
Springer
15 years 10 months ago
Ab Initio Whole Genome Shotgun Assembly with Mated Short Reads
Next Generation Sequencing (NGS) technologies are capable of reading millions of short DNA sequences both quickly and cheaply. While these technologies are already being used for r...
Paul Medvedev, Michael Brudno
BIBM
2010
IEEE
286views Bioinformatics» more  BIBM 2010»
14 years 7 months ago
Evaluation of short read metagenomic assembly
Advances in sequencing technologies have equipped researchers with the ability to sequence the collective genome of entire microbial communities commonly referred to as metagenomi...
Anveshi Charuvaka, Huzefa Rangwala
BMCBI
2010
103views more  BMCBI 2010»
14 years 10 months ago
A method of predicting changes in human gene splicing induced by genetic variants in context of cis-acting elements
Background: Polymorphic variants and mutations disrupting canonical splicing isoforms are among the leading causes of human hereditary disorders. While there is a substantial evid...
Alexander G. Churbanov, Igor Vorechovsky, Chindo H...