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BMCBI
2007
109views more  BMCBI 2007»
14 years 9 months ago
A cis-regulatory logic simulator
Background: A major goal of computational studies of gene regulation is to accurately predict the expression of genes based on the cis-regulatory content of their promoters. The d...
Robert D. Zeigler, Jason Gertz, Barak A. Cohen
JCB
2002
93views more  JCB 2002»
14 years 9 months ago
Unfolding of Microarray Data
The use of DNA microarrays for the analysis of complex biological samples is becoming a mainstream part of biomedical research. One of the most commonly used methods compares the ...
Andrew B. Goryachev, Pascale F. Macgregor, Aled M....
BMCBI
2008
134views more  BMCBI 2008»
14 years 9 months ago
Identification of transcription factor contexts in literature using machine learning approaches
Background: Availability of information about transcription factors (TFs) is crucial for genome biology, as TFs play a central role in the regulation of gene expression. While man...
Hui Yang, Goran Nenadic, John A. Keane
BMCBI
2005
169views more  BMCBI 2005»
14 years 9 months ago
MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes
Background: Cis-regulatory modules are combinations of regulatory elements occurring in close proximity to each other that control the spatial and temporal expression of genes. Th...
Voichita D. Marinescu, Isaac S. Kohane, Alberto Ri...
BMCBI
2007
165views more  BMCBI 2007»
14 years 9 months ago
Automatic reconstruction of a bacterial regulatory network using Natural Language Processing
Background: Manual curation of biological databases, an expensive and labor-intensive process, is essential for high quality integrated data. In this paper we report the implement...
Carlos Rodríguez Penagos, Heladia Salgado, ...