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BMCBI
2008
162views more  BMCBI 2008»
14 years 9 months ago
Background correction using dinucleotide affinities improves the performance of GCRMA
Background: High-density short oligonucleotide microarrays are a primary research tool for assessing global gene expression. Background noise on microarrays comprises a significan...
Raad Z. Gharaibeh, Anthony Fodor, Cynthia Gibas
CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
15 years 2 months ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
IMSCCS
2006
IEEE
15 years 3 months ago
Frequency Distribution of TATA Box and Extension Sequences on Human Promoters
Background: TATA box is one of the most important transcription factor binding sites. But the exact sequences of TATA box are still not very clear. Results: In this study, we cond...
Wei Shi, Wanlei Zhou
BMCBI
2005
77views more  BMCBI 2005»
14 years 9 months ago
Combining Affymetrix microarray results
Background: As the use of microarray technology becomes more prevalent it is not unusual to find several laboratories employing the same microarray technology to identify genes re...
John R. Stevens, R. W. Doerge
BMCBI
2010
136views more  BMCBI 2010»
14 years 9 months ago
Bias correction and Bayesian analysis of aggregate counts in SAGE libraries
Background: Tag-based techniques, such as SAGE, are commonly used to sample the mRNA pool of an organism's transcriptome. Incomplete digestion during the tag formation proces...
Russell L. Zaretzki, Michael A. Gilchrist, William...