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BMCBI
2008
161views more  BMCBI 2008»
14 years 9 months ago
Inferring gene expression dynamics via functional regression analysis
Background: Temporal gene expression profiles characterize the time-dynamics of expression of specific genes and are increasingly collected in current gene expression experiments....
Hans-Georg Müller, Jeng-Min Chiou, Xiaoyan Le...
CEC
2011
IEEE
13 years 9 months ago
Inferring transcriptional regulators for sets of co-expressed genes by multi-objective evolutionary optimization
Abstract—Higher organisms are able to respond to continuously changing external conditions by transducing cellular signals into specific regulatory programs, which control gene ...
Adrian Schröder, Clemens Wrzodek, Johannes Wo...
68
Voted
CCE
2005
14 years 9 months ago
Large-scale inference of the transcriptional regulation of Bacillus subtilis
This paper addresses the inference of the transcriptional regulatory network of Bacillus subtilis. Two inference approaches, a linear, additive model and a non-linear power-law mo...
Anshuman Gupta, Jeffrey D. Varner, Costas D. Maran...
110
Voted
BMCBI
2006
122views more  BMCBI 2006»
14 years 9 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
BMCBI
2007
174views more  BMCBI 2007»
14 years 9 months ago
Inferring activity changes of transcription factors by binding association with sorted expression profiles
Background: The identification of transcription factors (TFs) associated with a biological process is fundamental to understanding its regulatory mechanisms. From microarray data,...
Chao Cheng, Xiting Yan, Fengzhu Sun, Lei M. Li