One of the purposes of Systems Biology is the quantitative modeling of biochemical networks. In this effort, the use of dynamical mathematical models provides for powerful tools in...
The haplotype inference problem (HIP) asks to find a set of haplotypes which resolve a given set of genotypes. This problem is of enormous importance in many practical fields, su...
Michael R. Fellows, Tzvika Hartman, Danny Hermelin...
This paper presents a novel placement algorithm for timing optimization based on a new and powerful concept, which we term differential timing analysis. Recognizing that accurate ...
Amit Chowdhary, Karthik Rajagopal, Satish Venkates...
Background: Current approaches to parameter estimation are often inappropriate or inconvenient for the modelling of complex biological systems. For systems described by nonlinear ...
Background: Using microarray and sequencing platforms, a large number of copy number variations (CNVs) have been identified in humans. In practice, because our human genome is a d...