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» Inferring Genetic Networks from Microarray Data
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BMCBI
2007
144views more  BMCBI 2007»
14 years 11 months ago
Accelerated search for biomolecular network models to interpret high-throughput experimental data
Background: The functions of human cells are carried out by biomolecular networks, which include proteins, genes, and regulatory sites within DNA that encode and control protein e...
Suman Datta, Bahrad A. Sokhansanj
BMCBI
2010
125views more  BMCBI 2010»
14 years 11 months ago
Asymmetric microarray data produces gene lists highly predictive of research literature on multiple cancer types
Background: Much of the public access cancer microarray data is asymmetric, belonging to datasets containing no samples from normal tissue. Asymmetric data cannot be used in stand...
Noor B. Dawany, Aydin Tozeren
BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
14 years 11 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...
IPPS
2010
IEEE
14 years 9 months ago
Efficient and scalable parallel reconstruction of sibling relationships from genetic data in wild populations
Wild populations of organism are often difficult to study in their natural settings. Often, it is possible to infer mating information about these species by genotyping the offspri...
Saad I. Sheikh, Ashfaq A. Khokhar, Tanya Y. Berger...
BMCBI
2007
174views more  BMCBI 2007»
14 years 11 months ago
Inferring activity changes of transcription factors by binding association with sorted expression profiles
Background: The identification of transcription factors (TFs) associated with a biological process is fundamental to understanding its regulatory mechanisms. From microarray data,...
Chao Cheng, Xiting Yan, Fengzhu Sun, Lei M. Li