In this paper we present a novel expectation-maximization algorithm for inference of alternative splicing isoform frequencies from high-throughput transcriptome sequencing (RNA-Seq...
Marius Nicolae, Serghei Mangul, Ion I. Mandoiu, Al...
Background: As the use of microarray technology becomes more prevalent it is not unusual to find several laboratories employing the same microarray technology to identify genes re...
The genome projects have provided comprehensive information about the basic building blocks of life. The next challenge is to understand how biological functions emerge from compl...
Samik Ghosh, Preetam Ghosh, Kalyan Basu, Sajal K. ...
Background: Gene regulatory networks play essential roles in living organisms to control growth, keep internal metabolism running and respond to external environmental changes. Un...
Background: The development of software tools that analyze microarray data in the context of genetic knowledgebases is being pursued by multiple research groups using different me...