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» Inferring differentiation pathways from gene expression
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BMCBI
2006
133views more  BMCBI 2006»
14 years 9 months ago
Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae
Background: Signal recognition and information processing is a fundamental cellular function, which in part involves comprehensive transcriptional regulatory (TR) mechanisms carri...
Illés J. Farkas, Chuang Wu, Chakra Chennubh...
BIOCOMP
2008
14 years 11 months ago
Prediction of Protein Function Using Graph Container and Message Passing
We introduce a novel parameter called container flux, which is used to measure the information sharing capacity between two distinct nodes in a graph. Other useful information, bot...
Hongbo Zhou, Qiang Shawn Cheng, Mehdi Zargham
BMCBI
2010
95views more  BMCBI 2010»
14 years 9 months ago
Modelling p-value distributions to improve theme-driven survival analysis of cancer transcriptome datasets
Background: Theme-driven cancer survival studies address whether the expression signature of genes related to a biological process can predict patient survival time. Although this...
Esteban Czwan, Benedikt Brors, David Kipling
NAR
2011
290views Computer Vision» more  NAR 2011»
14 years 14 days ago
AHD2.0: an update version of Arabidopsis Hormone Database for plant systematic studies
Phytohormone studies enlightened our knowledge of plant responses to various changes. To provide a systematic and comprehensive view of genes participating in plant hormonal regul...
Zhiqiang Jiang, Xiao-Chuan Liu, Zhiyu Peng, Yinan ...
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BMCBI
2008
108views more  BMCBI 2008»
14 years 9 months ago
New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic backgroun
Background: Few genetic factors predisposing to the sporadic form of amyotrophic lateral sclerosis (ALS) have been identified, but the pathology itself seems to be a true multifac...
Silvana Penco, Massimo Buscema, Maria Cristina Pat...