We present an efficient, fully automated algorithm to assemble ESTs into full-length cDNA sequences that represent the complete coding regions of a gene. Our EST clustering algori...
Arthur Grossman, Charles Hauser, Hilary J. Holz, J...
Background: Normalization is essential in dual-labelled microarray data analysis to remove nonbiological variations and systematic biases. Many normalization methods have been use...
Huiling Xiong, Dapeng Zhang, Christopher J. Martyn...
Background: Publicly accessible EST libraries contain valuable information that can be utilized for studies of tissue-specific gene expression and processing of individual genes. ...
Abstract. Traditional sequence comparison by alignment applies a mutation model comprising two events, substitutions and indels (insertions or deletions) of single positions (SI). ...
Michael Sammeth, Thomas Weniger, Dag Harmsen, Jens...
One of the major goals of computational sequence analysis is to find sequence similarities, which could serve as evidence of structural and functional conservation, as well as of ...