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» Information Analysis of DNA Sequences
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91
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RECOMB
2001
Springer
15 years 6 months ago
DNA segmentation as a model selection process
Previous divide-and-conquer segmentation analyses of DNA sequences do not provide a satisfactory stopping criterion for the recursion. This paper proposes that segmentation be con...
Wentian Li
132
Voted
BMCBI
2006
143views more  BMCBI 2006»
15 years 1 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
124
Voted
NAR
2011
212views Computer Vision» more  NAR 2011»
14 years 4 months ago
The Sequence Read Archive
The combination of significantly lower cost and increased speed of sequencing has resulted in an explosive growth of data submitted into the primary next-generation sequence data ...
Rasko Leinonen, Hideaki Sugawara, Martin Shumway
BMCBI
2010
145views more  BMCBI 2010»
15 years 2 months ago
Clustering metagenomic sequences with interpolated Markov models
Background: Sequencing of environmental DNA (often called metagenomics) has shown tremendous potential to uncover the vast number of unknown microbes that cannot be cultured and s...
David R. Kelley, Steven L. Salzberg
RECOMB
2010
Springer
15 years 8 months ago
A Novel Abundance-Based Algorithm for Binning Metagenomic Sequences Using l-Tuples
Abstract. Metagenomics is the study of microbial communities sampled directly from their natural environment, without prior culturing. Among the computational tools recently develo...
Yu-Wei Wu, Yuzhen Ye