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» Information Analysis of DNA Sequences
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132
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BMCBI
2007
164views more  BMCBI 2007»
15 years 2 months ago
The Personal Sequence Database: a suite of tools to create and maintain web-accessible sequence databases
Background: Large molecular sequence databases are fundamental resources for modern bioscientists. Whether for project-specific purposes or sharing data with colleagues, it is oft...
Scott A. Givan, Christopher M. Sullivan, James C. ...
112
Voted
BMCBI
2010
101views more  BMCBI 2010»
15 years 2 months ago
Detection of copy number variation from array intensity and sequencing read depth using a stepwise Bayesian model
Background: Copy number variants (CNVs) have been demonstrated to occur at a high frequency and are now widely believed to make a significant contribution to the phenotypic variat...
Zhengdong D. Zhang, Mark B. Gerstein
ICC
2007
IEEE
117views Communications» more  ICC 2007»
15 years 8 months ago
Applying Techniques from Frame Synchronization for Biological Sequence Analysis
— During the last years, the amount of genetic data available has increased rapidly which creates the demand for advanced techniques for their interpretation. In the following, w...
Johanna Weindl, Joachim Hagenauer
BMCBI
2004
98views more  BMCBI 2004»
15 years 1 months ago
STING Millennium Suite: integrated software for extensive analyses of 3d structures of proteins and their complexes
Background: The integration of many aspects of protein/DNA structure analysis is an important requirement for software products in general area of structural bioinformatics. In fa...
Roberto H. Higa, Roberto C. Togawa, Arnaldo J. Mon...
119
Voted
BMCBI
2006
152views more  BMCBI 2006»
15 years 1 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...