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» Information Analysis of DNA Sequences
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BMCBI
2010
190views more  BMCBI 2010»
15 years 2 months ago
A parallel and incremental algorithm for efficient unique signature discovery on DNA databases
Background: DNA signatures are distinct short nucleotide sequences that provide valuable information that is used for various purposes, such as the design of Polymerase Chain Reac...
Hsiao Ping Lee, Tzu-Fang Sheu, Chuan Yi Tang
BMCBI
2004
146views more  BMCBI 2004»
15 years 1 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
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BMCBI
2006
195views more  BMCBI 2006»
15 years 1 months ago
CAFTAN: a tool for fast mapping, and quality assessment of cDNAs
Background: The German cDNA Consortium has been cloning full length cDNAs and continued with their exploitation in protein localization experiments and cellular assays. However, t...
Coral del Val, Vladimir Yurjevich Kuryshev, Karl-H...
BIOINFORMATICS
2010
170views more  BIOINFORMATICS 2010»
15 years 2 months ago
Joint estimation of DNA copy number from multiple platforms
DNA copy number variants (CNV) are gains and losses of segments of chromosomes, and comprise an important class of genetic variation. Recently, various microarray hybridization ba...
Nancy R. Zhang, Yasin Senbabaoglu, Jun Z. Li
BIB
2010
103views more  BIB 2010»
14 years 11 months ago
Challenges of sequencing human genomes
Massively parallel sequencing technologies continue to alter the study of human genetics. As the cost of sequencing declines, next-generation sequencing (NGS) instruments and data...
Daniel C. Koboldt, Li Ding, Elaine R. Mardis, Rich...