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BMCBI
2008
111views more  BMCBI 2008»
15 years 6 months ago
VisualRepbase: an interface for the study of occurrences of transposable element families
Background: Repbase is a reference database of eukaryotic repetitive DNA, which includes prototypic sequences of repeats and basic information described in annotations. Repbase al...
Sébastien Tempel, Matthew Jurka, Jerzy Jurk...
BMCBI
2010
113views more  BMCBI 2010»
15 years 6 months ago
Use of historic metabolic biotransformation data as a means of anticipating metabolic sites using MetaPrint2D and Bioclipse
Background: Predicting metabolic sites is important in the drug discovery process to aid in rapid compound optimisation. No interactive tool exists and most of the useful tools ar...
Lars Carlsson, Ola Spjuth, Samuel Adams, Robert C....
BMCBI
2010
142views more  BMCBI 2010»
15 years 6 months ago
pplacer: linear time maximum-likelihood and Bayesian phylogenetic placement of sequences onto a fixed reference tree
Background: Likelihood-based phylogenetic inference is generally considered to be the most reliable classification method for unknown sequences. However, traditional likelihood-ba...
Frederick A. Matsen III, Robin B. Kodner, E. Virgi...
BMCBI
2008
175views more  BMCBI 2008»
15 years 6 months ago
Comprehensive inventory of protein complexes in the Protein Data Bank from consistent classification of interfaces
Background: Protein-protein interactions are ubiquitous and essential for all cellular processes. High-resolution X-ray crystallographic structures of protein complexes can reveal...
Andrew J. Bordner, Andrey A. Gorin
BMCBI
2008
106views more  BMCBI 2008»
15 years 6 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
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