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BMCBI
2010
214views more  BMCBI 2010»
15 years 3 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
BMCBI
2010
165views more  BMCBI 2010»
15 years 3 months ago
Multivariate meta-analysis of proteomics data from human prostate and colon tumours
Background: There is a vast need to find clinically applicable protein biomarkers as support in cancer diagnosis and tumour classification. In proteomics research, a number of met...
Lina Hultin Rosenberg, Bo Franzén, Gert Aue...
BMCBI
2006
166views more  BMCBI 2006»
15 years 3 months ago
SEQOPTICS: a protein sequence clustering system
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
Yonghui Chen, Kevin D. Reilly, Alan P. Sprague, Zh...
BMCBI
2006
179views more  BMCBI 2006»
15 years 3 months ago
Accurate and unambiguous tag-to-gene mapping in serial analysis of gene expression
Background: In this study, we present a robust and reliable computational method for tag-togene assignment in serial analysis of gene expression (SAGE). The method relies on curre...
Rodrigo Malig, Cristian Varela, Eduardo Agosin, Fr...
BMCBI
2006
161views more  BMCBI 2006»
15 years 3 months ago
A method for rapid similarity analysis of RNA secondary structures
Background: Owing to the rapid expansion of RNA structure databases in recent years, efficient methods for structure comparison are in demand for function prediction and evolution...
Na Liu, Tianming Wang
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